Using optogenetics to visualize histone H2AX phosphorylation in living cells with high precision

Illustration of the Eucor Seed Money project ‘Using optogenetics to visualize histone H2AX phosphorylation in living cells with high precision’

This team of biologists is developing a light-sensitive form of a nanobody that specifically binds to the phosphorylated H2AX protein and analysing it in living cells. The aim is to better understand the role that this post-translational modification plays in DNA repair. The project is supported by Eucor – The European Campus in the “Research and Innovation” category of the Seed Money scheme.

Interview with Prof. Barbara Di Ventura, project carrier.

Summary of the project “Using optogenetics to visualize histone H2AX phosphorylation in living cells with high precision” [170.2 KiB]

Contact:

Freiburg: Barbara Di Ventura
Strasbourg: Étienne Weiss